英文邮件的开头和结尾可以根据不同的场合和关系亲疏进行选择，以下是一些常见的表达方式：

开头

非正式场合

Hi__, [收件人姓名]

Hey__, [收件人姓名]

How are you doing？

I hope this email finds you well.

正式场合

Dear [收件人姓名],

Dear Mr./Ms. [姓氏],

Dear Madame,

Dear Sir,

结尾

非正式场合

Thanks,

Thank you,

Best regards,

Kind regards,

Yours sincerely,

Best wishes,

正式场合

Sincerely,

Yours truly,

Best regards,

Kind regards,

Thank you very much for your time and assistance. I look forward to your guidance on this matter.

示例

正式邮件开头：

```

Dear Mr. Smith,

I hope this email finds you in good health.

```

正式邮件结尾：

```

Thank you very much for your prompt response. I look forward to hearing from you soon.

Sincerely,

[你的名字]

```

非正式邮件开头：

```

Hi John,

How's it going?

```

非正式邮件结尾：

```

Thanks a bunch!

Best,

[你的名字]

```

建议

了解收件人：根据收件人的身份和关系亲疏选择合适的称呼语和结束语。

保持简洁：邮件开头和结尾应简洁明了，避免冗长。

礼貌用语：使用礼貌用语可以展现你的专业素养和尊重。